<!DOCTYPE html>
<html class="client-nojs vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-0 vector-toc-not-available vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-0 skin-theme-clientpref-day vector-sticky-header-enabled" lang="de" dir="ltr"><head>
<meta charset="UTF-8">
<title>Distamycin</title>
<meta name="viewport" content="width=device-width, initial-scale=1.0">
<link rel="icon" type="image/png" href="./_res_/favicon.png">
<link rel="canonical" href="https://de.wikipedia.org/wiki/Distamycin"> <link href="./_mw_/ext.cite.styles.css" rel="stylesheet" type="text/css">
<link href="./_mw_/ext.wikimediamessages.styles.css" rel="stylesheet" type="text/css">
<link href="./_mw_/skins.vector.icons.css" rel="stylesheet" type="text/css">
<link href="./_mw_/skins.vector.search.codex.styles.css" rel="stylesheet" type="text/css">
<link href="./_mw_/skins.vector.styles.css" rel="stylesheet" type="text/css">
<meta name="ResourceLoaderDynamicStyles" content="">
<link href="./_mw_/ext.gadget.citeRef.css" rel="stylesheet" type="text/css">
<link href="./_mw_/ext.gadget.defaultPlainlinks.css" rel="stylesheet" type="text/css">
<link href="./_mw_/ext.gadget.dewikiCommonHide.css" rel="stylesheet" type="text/css">
<link href="./_mw_/ext.gadget.dewikiCommonLayout.css" rel="stylesheet" type="text/css">
<link href="./_mw_/ext.gadget.dewikiCommonStyle.css" rel="stylesheet" type="text/css">
<link href="./_mw_/ext.gadget.dewikiDarkmode.css" rel="stylesheet" type="text/css">
<link href="./_mw_/ext.gadget.dewikiResponsive.css" rel="stylesheet" type="text/css">
<link href="./_mw_/ext.gadget.specialSearch.css" rel="stylesheet" type="text/css">
<link rel="stylesheet" type="text/css" href="./_mw_/site.styles.css">
<link rel="stylesheet" type="text/css" href="./_mw_/noscript.css">
<link rel="stylesheet" type="text/css" href="./_res_/footer.css">
<link rel="stylesheet" type="text/css" href="./_res_/vector-2022.css">
</head>
<body class="skin--responsive skin-vector skin-vector-search-vue mediawiki ltr sitedir-ltr mw-hide-empty-elt ns-0 ns-subject page-Distamycin rootpage-Distamycin skin-vector-2022 action-view">
<div class="mw-page-container">
<div class="mw-page-container-inner">
<div class="mw-content-container">
<main id="content" class="mw-body">
<header class="mw-body-header vector-page-titlebar">
<h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Distamycin</span></h1>
</header>
<a id="top"></a>
<div id="bodyContent" class="vector-body ve-init-mw-desktopArticleTarget-targetContainer" aria-labelledby="firstHeading" data-mw-ve-target-container="">
<div id="contentSub">
<div id="mw-content-subtitle"></div>
</div>
<div id="mw-content-text" class="mw-body-content mw-content-ltr" lang="de" dir="ltr"><div class="mw-content-ltr mw-parser-output" lang="de" dir="ltr"><table class="wikitable infobox float-right" id="Vorlage_Infobox_Chemikalie" style="font-size:90%; margin-top:0; width:350px;" summary="Infobox Chemikalie">
<tbody><tr>
<th colspan="2" style="background:#FFDEAD; color:#202122;">Strukturformel
</th></tr>
<tr>
<td colspan="2" class="hintergrundfarbe-basis skin-invert-image" style="text-align:center;"><span typeof="mw:File"></span>
</td></tr>
<tr>
<th colspan="2" style="background:#FFDEAD; color:#202122;">Allgemeines
</th></tr>
<tr>
<td style="width:33%;">Name
</td>
<td>Distamycin
</td></tr>
<tr>
<td>Andere Namen
</td>
<td>
<ul><li>Distamycin A</li>
<li>Herperetin</li>
<li>Stallimycin</li>
<li>3-[1-Methyl-4-[1-methyl-4-[1-methyl-4-(formylamino)pyrrol-2-carboxamido]-pyrrol-2-carboxamid]pyrrol-2-carboxamid]propionamidin-Hydrochlorid</li></ul>
</td></tr>
<tr>
<td><a href="Summenformel" title="Summenformel">Summenformel</a>
</td>
<td>C<sub>22</sub>H<sub>27</sub>N<sub>9</sub>O<sub>4</sub> · HCl
</td></tr>
<tr>
<td>Kurzbeschreibung
</td>
<td>
<p>gelber Feststoff<sup id="cite_ref-Sigma_1-0" class="reference"><a href="#cite_note-Sigma-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>
</p>
</td></tr>
<tr>
<th colspan="2" style="background:#FFDEAD; color:#202122;">Externe Identifikatoren/Datenbanken
</th></tr>
<tr>
<td colspan="2" style="padding:0;">
<table class="mw-collapsible mw-collapsed wikitable" data-expandtext="+" data-collapsetext="−" style="border-top:none; margin:-1px; width:calc(100% + 2px);">
<tbody><tr>
<td style="width:33%;"><a href="CAS-Nummer" title="CAS-Nummer">CAS-Nummer</a>
</td>
<td><span title="Untervorlage eingebunden: CASRN"></span><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=6576-51-8">6576-51-8</a><span class="editoronly" style="display:none;"></span>
</td>
<td style="background:#FFDEAD; color:#202122; border-top:1px solid #FFDEAD; padding:0.2em 0; vertical-align:bottom; width:5%;">
</td></tr>
<tr>
<td><a href="EG-Nummer" title="EG-Nummer">EG-Nummer</a>
</td>
<td colspan="2">229-505-6
</td></tr>
<tr>
<td><a href="Europ%C3%A4ische_Chemikalienagentur" title="Europäische Chemikalienagentur">ECHA</a>-InfoCard
</td>
<td colspan="2"><a rel="nofollow" class="external text" href="https://www.echa.europa.eu/de/substance-information/-/substanceinfo/100.026.823">100.026.823</a>
</td></tr>
<tr>
<td><a href="PubChem" title="PubChem">PubChem</a>
</td>
<td colspan="2"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/24894001">24894001</a>
</td></tr>
<tr>
<td><a href="ChemSpider" title="ChemSpider">ChemSpider</a>
</td>
<td colspan="2"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.25036768.html">25036768</a>
</td></tr>
<tr>
<td style="border-right:1px solid #a2a9b1;"><a href="Wikidata" title="Wikidata">Wikidata</a>
</td>
<td colspan="2"><a href="https://www.wikidata.org/wiki/Q15965140" class="extiw external" title="d:Q15965140">Q15965140</a>
</td></tr></tbody></table>
</td></tr>
<tr>
<th colspan="2" style="background:#FFDEAD; color:#202122;">Eigenschaften
</th></tr>
<tr>
<td><a href="Molare_Masse" title="Molare Masse">Molare Masse</a>
</td>
<td>517,97 g·<a href="Mol" title="Mol">mol</a><sup>−1</sup>
</td></tr>
<tr>
<td><a href="Aggregatzustand" title="Aggregatzustand">Aggregatzustand</a>
</td>
<td>
<p>fest<sup id="cite_ref-Sigma_1-1" class="reference"><a href="#cite_note-Sigma-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>
</p>
</td></tr>
<tr>
<td><a href="Schmelzpunkt" title="Schmelzpunkt">Schmelzpunkt</a>
</td>
<td>
<p>>300 <a href="Grad_Celsius" title="Grad Celsius">°C</a><sup id="cite_ref-Sigma_1-2" class="reference"><a href="#cite_note-Sigma-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>
</p>
</td></tr>
<tr>
<th colspan="2" style="background:#FFDEAD; color:#202122;">Sicherheitshinweise
</th></tr>
<tr>
<td colspan="2">
<table cellspacing="0" cellpadding="2" style="width:100%;">
<tbody><tr>
<td colspan="2" style="text-align:center"><b><a href="Global_harmonisiertes_System_zur_Einstufung_und_Kennzeichnung_von_Chemikalien" title="Global harmonisiertes System zur Einstufung und Kennzeichnung von Chemikalien">GHS-Gefahrstoffkennzeichnung</a></b><sup id="cite_ref-Sigma_1-3" class="reference"><a href="#cite_note-Sigma-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>
<table class="hintergrundfarbe-neutral" style="text-align:center; margin-left:auto; margin-right:auto; display:flex; justify-content:center;">
<tbody><tr>
<td><span typeof="mw:File"><a href="Global_harmonisiertes_System_zur_Einstufung_und_Kennzeichnung_von_Chemikalien#Übersicht:_EU-Gefahrensymbole,_UN/GHS-Gefahrenpiktogramme,_UN/ADR-Gefahrensymbole" title="07 – Achtung"></a></span>
</td></tr></tbody></table>
<p>
</p>
</td></tr>
<tr>
<td rowspan="2" width="33%" style="border-top:1px #A7A7A7 dashed; border-right:1px #A7A7A7 dashed;"><a href="H-_und_P-S%C3%A4tze" title="H- und P-Sätze">H- und P-Sätze</a>
</td>
<td style="border-top:1px #A7A7A7 dashed;">H: <span title="Untervorlage eingebunden: H-Sätze"></span><a href="H-_und_P-S%C3%A4tze#H-Sätze" title="H- und P-Sätze"><span style="display:inline-block;"><span style="color:#ff5400; border-bottom:1px dotted #ff5400;" title="Kann allergische Hautreaktionen verursachen.">317</span></span></a>
</td></tr>
<tr>
<td style="border-top:1px #A7A7A7 dashed;">P: <span title="Untervorlage eingebunden: P-Sätze"></span><a href="H-_und_P-S%C3%A4tze#P-Sätze" title="H- und P-Sätze"><span style="display:inline-block;"><span style="color:#ff5400; border-bottom:1px dotted #ff5400;" title="Schutzhandschuhe/Schutzkleidung/Augenschutz/Gesichtsschutz/Gehörschutz/… tragen.
(Geänderter Text seit Inkraftreten der „12. Anpassung an den Technischen Fortschritt“ am 17. Oktober 2020)">280</span></span></a><sup id="cite_ref-Sigma_1-4" class="reference"><a href="#cite_note-Sigma-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>
</td></tr>
</tbody></table>
</td></tr>
<tr>
<td colspan="2" style="background:#FFDEAD; color:#202122; font-size:80%; text-align:center; line-height:150%; padding:.25em;">Wenn nicht anders vermerkt, gelten die angegebenen Daten bei <a href="Standardbedingungen" title="Standardbedingungen">Standardbedingungen</a> (0 °C, 1000 hPa).
</td></tr></tbody></table><p><span class="editoronly" style="display:none;"></span>
</p><p><b>Distamycin</b> ist ein <a href="Polyamid" class="mw-redirect" title="Polyamid">Polyamid</a>-<a href="Antibiotikum" title="Antibiotikum">Antibiotikum</a>, das an die kleine Furche einer <a href="DNA" class="mw-redirect" title="DNA">DNA</a>-<a href="Doppelhelix" title="Doppelhelix">Doppelhelix</a> bindet.<sup id="cite_ref-PMID_23507040_2-0" class="reference"><a href="#cite_note-PMID_23507040-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup>
</p>
<div class="mw-heading mw-heading2"><h2 id="Eigenschaften">Eigenschaften</h2></div>
<p>Distamycin gehört zur Klasse <a href="Pyrrol" title="Pyrrol">Pyrrol</a>-<a href="Amidin" class="mw-redirect" title="Amidin">Amidin</a>-Antibiotika und ist ein Analogon von <a href="Netropsin" title="Netropsin">Netropsin</a> und den <a href="Lexitropsine" title="Lexitropsine">Lexitropsinen</a>. Im Gegensatz zu Netropsin besitzt Distamycin drei N-Methyl-Pyrrol-Einheiten. Distamycin wird aus <i>Streptomyces distallicus</i> isoliert. Es bindet bevorzugt an AT-reiche <a href="DNA-Sequenz" class="mw-redirect" title="DNA-Sequenz">DNA-Sequenzen</a> und Tetraden aus [TGGGGT]<sub>4</sub>.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup>
</p><p>Distamycin hemmt die <a href="Transkription_(Biologie)" title="Transkription (Biologie)">Transkription</a> und erhöht die Aktivität der <a href="Topoisomerase" title="Topoisomerase">Topoisomerase</a> II.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup>
</p><p>Verschiedene Derivate von Distamycin werden als <a href="Alkylanzien" title="Alkylanzien">Alkylanzien</a> zur Behandlung von <a href="Tumor" title="Tumor">Tumoren</a> untersucht.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-PMID_23507040_2-1" class="reference"><a href="#cite_note-PMID_23507040-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Distamycinderivate mit <a href="Fluorophor" class="mw-redirect" title="Fluorophor">Fluorophoren</a> werden zur <a href="Fluoreszenzmarkierung" title="Fluoreszenzmarkierung">Fluoreszenzmarkierung</a> von doppelsträngiger DNA verwendet.<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup>
</p><p>Distamycin ist <a href="Hygroskopisch" class="mw-redirect" title="Hygroskopisch">hygroskopisch</a>, <a href="Hydrolyse" title="Hydrolyse">hydrolyse</a>-, frost- und lichtempfindlich. Der <a href="Extinktionskoeffizient" title="Extinktionskoeffizient">Extinktionskoeffizient</a> beträgt 37.000 M<sup>−1</sup> cm<sup>−1</sup> bei einer <a href="Wellenl%C3%A4nge" title="Wellenlänge">Wellenlänge</a> von 303 nm.
</p>
<div class="mw-heading mw-heading2"><h2 id="Einzelnachweise">Einzelnachweise</h2></div>
<ol class="references">
<li id="cite_note-Sigma-1"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-Sigma_1-0">a</a></sup> <sup><a href="#cite_ref-Sigma_1-1">b</a></sup> <sup><a href="#cite_ref-Sigma_1-2">c</a></sup> <sup><a href="#cite_ref-Sigma_1-3">d</a></sup> <sup><a href="#cite_ref-Sigma_1-4">e</a></sup></span> <span class="reference-text">Datenblatt <span style="font-style:italic;"><a rel="nofollow" class="external text" href="https://www.sigmaaldrich.com/catalog/product/SIGMA/d6135">Distamycin hydrochloride</a></span> bei <a href="Sigma-Aldrich" title="Sigma-Aldrich">Sigma-Aldrich</a>, abgerufen am 24. November 2013 (<a rel="nofollow" class="external text" href="https://www.sigmaaldrich.com/DE/de/sds/SIGMA/d6135?userType=anonymous">PDF</a>).<span class="editoronly" style="display:none;"></span></span>
</li>
<li id="cite_note-PMID_23507040-2"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-PMID_23507040_2-0">a</a></sup> <sup><a href="#cite_ref-PMID_23507040_2-1">b</a></sup></span> <span class="reference-text">M. P. Barrett, C. G. Gemmell, C. J. Suckling: <i>Minor groove binders as anti-infective agents.</i> In: <i><a href="Pharmacology_%26_Therapeutics" title="Pharmacology & Therapeutics">Pharmacology & Therapeutics</a>.</i> Band 139, Nummer 1, Juli 2013, S. 12–23. <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1016/j.pharmthera.2013.03.002">10.1016/j.pharmthera.2013.03.002</a></span>. <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/23507040?dopt=Abstract">PMID 23507040</a>.</span>
</li>
<li id="cite_note-3"><span class="mw-cite-backlink"><a href="#cite_ref-3">↑</a></span> <span class="reference-text">M. L. Kopka, C. Yoon, D. Goodsell, P. Pjura, R. E. Dickerson: <i>The molecular origin of DNA-drug specificity in netropsin and distamycin.</i> In: <i><a href="Proceedings_of_the_National_Academy_of_Sciences_of_the_United_States_of_America" title="Proceedings of the National Academy of Sciences of the United States of America">Proceedings of the National Academy of Sciences of the United States of America</a>.</i> Band 82, Nummer 5, März 1985, S. 1376–1380. <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/2983343?dopt=Abstract">PMID 2983343</a>. <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC397264/">PMC 397264</a> (freier Volltext).</span>
</li>
<li id="cite_note-4"><span class="mw-cite-backlink"><a href="#cite_ref-4">↑</a></span> <span class="reference-text">B. Pagano, I. Fotticchia, S. De Tito, C. A. Mattia, L. Mayol, E. Novellino, A. Randazzo, C. Giancola: <i>Selective Binding of Distamycin A Derivative to G-Quadruplex Structure [d(TGGGGT)](4).</i> In: <i>Journal of nucleic acids.</i> 2010. <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.4061/2010%2F247137">10.4061/2010/247137</a></span>. <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/20725616?dopt=Abstract">PMID 20725616</a>. <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915651/">PMC 2915651</a> (freier Volltext).</span>
</li>
<li id="cite_note-5"><span class="mw-cite-backlink"><a href="#cite_ref-5">↑</a></span> <span class="reference-text">P. Majumder, A. Banerjee, J. Shandilya, P. Senapati, S. Chatterjee, T. K. Kundu, D. Dasgupta: <i>Minor groove binder distamycin remodels chromatin but inhibits transcription.</i> In: <i><a href="PLOS_ONE" title="PLOS ONE">PLOS ONE</a>.</i> Band 8, Nummer 2, 2013, S. e57693. <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1371/journal.pone.0057693">10.1371/journal.pone.0057693</a></span>. <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/23460895?dopt=Abstract">PMID 23460895</a>. <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584068/">PMC 3584068</a> (freier Volltext).</span>
</li>
<li id="cite_note-6"><span class="mw-cite-backlink"><a href="#cite_ref-6">↑</a></span> <span class="reference-text">M. Fesen, Y. Pommier: <i>Mammalian topoisomerase II activity is modulated by the DNA minor groove binder distamycin in simian virus 40 DNA.</i> In: <i><a href="The_Journal_of_Biological_Chemistry" class="mw-redirect" title="The Journal of Biological Chemistry">The Journal of Biological Chemistry</a>.</i> Band 264, Nummer 19, Juli 1989, S. 11354–11359. <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/2544590?dopt=Abstract">PMID 2544590</a>.</span>
</li>
<li id="cite_note-7"><span class="mw-cite-backlink"><a href="#cite_ref-7">↑</a></span> <span class="reference-text">P. G. Baraldi, D. Preti, F. Fruttarolo, M. A. Tabrizi, R. Romagnoli: <i>Hybrid molecules between distamycin A and active moieties of antitumor agents.</i> In: <i><a href="Bioorganic_%26_Medicinal_Chemistry" title="Bioorganic & Medicinal Chemistry">Bioorganic & Medicinal Chemistry</a>.</i> Band 15, Nummer 1, Januar 2007, S. 17–35. <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1016/j.bmc.2006.07.004">10.1016/j.bmc.2006.07.004</a></span>. <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/17081759?dopt=Abstract">PMID 17081759</a>.</span>
</li>
<li id="cite_note-8"><span class="mw-cite-backlink"><a href="#cite_ref-8">↑</a></span> <span class="reference-text">T. Vaijayanthi, T. Bando, G. N. Pandian, H. Sugiyama: <i>Progress and prospects of pyrrole-imidazole polyamide-fluorophore conjugates as sequence-selective DNA probes.</i> In: <i><a href="ChemBioChem" title="ChemBioChem">ChemBioChem</a>.</i> Band 13, Nummer 15, Oktober 2012, S. 2170–2185. <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1002/cbic.201200451">10.1002/cbic.201200451</a></span>. <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/23023993?dopt=Abstract">PMID 23023993</a>.</span>
</li>
</ol>
<div class="hintergrundfarbe1 rahmenfarbe1 navigation-not-searchable" style="border-top-style: solid; border-top-width: 1px; clear: both; font-size:95%; margin-top:1em; padding: 0.25em; overflow: hidden; word-break: break-word; word-wrap: break-word;" id="Vorlage_Gesundheitshinweis"><div class="noviewer noresize nomobile" style="display: table-cell; padding-bottom: 0.2em; padding-left: 0.25em; padding-right: 1em; padding-top: 0.2em; vertical-align: middle;" aria-hidden="true" role="presentation"><span typeof="mw:File"></span></div>
<div style="display: table-cell; vertical-align: middle; width: 100%;">
<div>
Dieser Artikel behandelt ein Gesundheitsthema. Er dient weder der Selbstdiagnose noch wird dadurch eine Diagnose durch einen Arzt ersetzt. Bitte hierzu den Hinweis zu Gesundheitsthemen beachten!</div>
</div></div></div><!--htdig_noindex--><div><div class="zim-footer">
Dieser Artikel wurde von <a class="external text" title="Zuletzt bearbeitet am 2021-05-27" href="https://de.wikipedia.org/wiki/?title=Distamycin&oldid=212428690">Wikipedia</a> herausgegeben. Der Text ist unter <a class="external text" href="https://creativecommons.org/licenses/by-sa/4.0/deed.de">Creative Commons Attribution-Share Alike 4.0</a> verfügbar, sofern nicht anders angegeben. Für die Mediendateien können zusätzliche Bedingungen gelten.
</div>
</div><!--/htdig_noindex--></div>
</div>
</main>
</div>
</div>
</div>
<script src="./_webp_/webpHandler.js"></script>
</body></html>